NEFH anticorps
Aperçu rapide pour NEFH anticorps (ABIN6297897)
Antigène
Voir toutes NEFH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse anti-Human/Mouse/Rat/Chicken/Pig Neurofilament Antibody Cocktail [IHC only]
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Specificité
- Cytoplasmic
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Purification
- Triton-X 100 insoluble proteins of rat brain (RT-97) and Neurofilaments from porcine spinal cord (NR-4) were used as the immunogen for the Neurofilament antibody cocktail.
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Immunogène
- Triton-X 100 insoluble proteins of rat brain (RT-97) and Neurofilaments from porcine spinal cord (NR-4) were used as the immunogen for the Neurofilament antibody cocktail.
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Indications d'application
- Prediluted format : incubate for 30 min at RT (2)
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Restrictions
- For Research Use only
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Buffer
- Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
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Autre désignation
- Neurofilament heavy polypeptide
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Sujet
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Target Description: This mAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and cell carcinomas of the lung also express neurofilament.
Gene Symbol: NEFH///KIAA0845///NFH
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ID gène
- 4744
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UniProt
- P12036
Antigène
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